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Gynecomastia along with other side effects like hypertension, suppression of natural testosterone production, alopecia, acne, and water retention are some of the most dreaded side effects that come along with taking Androgenic Anabolic steroids. The good news is that Exedrol can literally treat and even prevent all these side effects from occurring in the first place.
Exedrol (active substance – exemestanum) is an anti-estrogen but it belongs to the family of drugs known as aromatase inhibitors. Aromatase inhibitors inhibit the enzyme aromatase thus preventing anabolic androgenic steroids from being aromatised into estrogens. This is how Exedrol achieves its anti-estrogenic effects and prevent the above estrogen related side effects.
Exedrol is found in tablet form and apart from its anti-estrogenic side effects, it greatly boosts the levels of testosterone and other gonadotropic hormones in the blood. Exedrol also lessens the recovery period of the athlete by lowering the estrogenic depression of the hypothalamic-pituitary-testicular axis.
Exemestane is an irreversible steroidal aromatase inhibitor, structurally related to the natural substrate, androstendione. Oral exemestane significantly decreased estrogen levels starting at a dose of 5 mg with a maximum suppression (> 90%) at a dose of 10-25 mg. In postmenopausal breast cancer patients treated with a daily dose of 25 mg, the effect of whole body aromatase was reduced by 98%.
Exemestane does not exhibit progestogenic or estrogenic activity. Especially at high doses, a mild androgenic activity was probably due to the 17-hydroderivative. In clinical trials with repeated daily doses, exemestane did not show detectable effects on cortisol or aldosterone biosynthesis of the adrenal glands, thus demonstrating its selectivity against other enzymes involved in the synthesis of steroid hormones.
Therefore, substitution therapy with glucocorticoids or mineralocorticoids is not necessary. A slight, dose-independent increase in serum LH and FSH levels has been observed even at low doses: this effect is however predictable for this class of drugs and is probably the result of pituitary feedback the decrease in estrogen concentration that stimulates the pituitary secretion.
Exemestane was generally well tolerated in all clinical trials with exemestane at a standard dose of 25 mg/day, and the reactions various were generally mild to moderate. Despite this, side effects such as rare thrombocytopenia, leukopenia, anorexia, insomnia, depression, headache, drowsiness, flushing, nausea, abdominal pain, vomiting, constipation, dyspepsia, diarrhea, gastric ulcer, increased liver function, increased activity of enzymes, bilirubin, alkaline phosphatase, hepatitis, hepatitis Rash, alopecia, pain in the joints and muscles, osteoporosis, fractures, fatigue, asthenia can occur.
The recommended daily dosage of Exedrol to treat estrogenic side effects is 25mg. This dose should be taken until the symptoms subside. Afterwards you can then lower the dosage to the preventive one.
Well added in Wess, there is a little fat. I train 4 times a week, in 2 months I added about 10 kg. Friends have not seen me for 1 week and ofigeli as I grew up I say that I eat protein and porridge))
Martin Martinez –
A very effective drug Balkan Exedrol! Weight gain was confident but moderate, no weight jumps and no side effects!