Detailed product information can be found here

BP Testosterona P (Propandrol) 1 ml by Balkan Pharmaceuticals is almost the same like Testosterone Enanthate. The main difference is that it has a much shorter time frame for action – only 1-2 days. But administering testosterone propionate is retained much less water. The drug acts immediately after administration.

Testosterone replacement therapy for male hypogonadism, when testosterone deficiency was confirmed by clinical features and biochemical tests. It is used as substitution therapy in castrated adults and those who are hypogonadal due to pituitary or testicular disease.

MEDICAL ACTION

Pharmacotherapeutic group: androgens, 3-oxoandrosten derivatives, ATC code: G03B A03.

Testosterone is the most important male androgen synthesized mainly in the testicles, and to a lesser extent in the cortex of the adrenal glands.

Testosterone is responsible for expressing male characteristics during fetal life, early childhood and puberty development, and subsequently to maintain male phenotype and androgen-dependent functions (e.g., spermatogenesis, accessory sexual glands).

Insufficient testosterone secretion leads to male hypogonadism characterized by low serum testosterone concentrations. Signs and symptoms associated with male hypogonadism include, but are not limited to, erectile dysfunction and decreased sexual desire, fatigue, depressive states, and a lack of secondary sexual characteristics, incomplete development or regression, increased risk of osteoporosis, visceral fat and a decrease in weak body mass and muscle strength.

Exogenous androgen are used to improve endogenous testosterone deficiency levels and associated signs and symptoms.

Depending on the target organ, the testosterone activity spectrum is especially androgenic (eg prostate, seminal vesicles, epididym) or anabolic protein (muscle, bone, hematopoietic, kidney, liver).

The effects of testosterone in certain organs occur after the peripheral conversion of testosterone to estradiol, which binds to estrogen receptors in the target cell nucleus, for example the pituitary, fat, brain, bones and Leydig testicular cells.

Hypogonadal androgens reduce body fat, increase lean body mass, muscle strength, and prevent bone loss. Androgen can improve sexual function and can exert positive psychotropic effects.

SIDE EFFECTS

Like all medicines, Propandrol can cause side effects, although not everybody gets them. If any of the side effects gets serious, tell your doctor or pharmacist. The most common side effects (may affect up to 1 in 10 people) are acne, abnormally high abnormal red blood cell counts, weight gain, hot flashes, increase of prostate specific antigen (increase of biochemical index in blood), increased prostate size and associated problems, increased erections and pain at the site of administration.

DOSAGE

Intramuscularly deep. The injections should be administered very slowly (for two minutes). The dose is determined individually depending on the patient’s indications and reactivity.

Men in hypogonadism are given 50 mg 2-3 times a week. In the case of delayed puberty and cryptorchidism, 50 mg per week is administered.

The contents of the ampoule will be injected intramuscularly after the opening, the remaining solution will be discarded. Propandol solution for injection in vials may be used several times after the first injection provided that the vial cap was not removed and the remaining contents remained hermetically sealed.