Esculap (Tadalafil) – an oral drug for treatment of erectile dysfunction. The drug increases the blood flow to the penis at the time of sexual stimulation that induces erection thus treating the erectile dysfunction and increasing libido.
If speaking about pulmonary arterial hypertension (PAH), Tadalafil relaxes the blood vessels in the lungs and blood begins to flow more easily.
Also it is used for treatment of and the initial prostatic hyperplasia which has such symptoms as difficult or painful urinating and urinary frequency and urgency among men.
Tadalafil improves erection and the possibility of successful sex. The medicine is valid for 36 hours. The effect is still 16 minutes after drug administration in the presence of sexual arousal.
Tadalafil in healthy individuals did not cause significant changes in systolic and diastolic blood pressure.
The action of the Balkan Esculap (Tadalafil) on PDE5 is more active than other phosphor-diasterates. Tadalafil is 10,000 times more potent for PDE5 than for PDE1, PDE2 and PDE4, which are in the heart, brain, blood vessels, liver and other organs. Tadalafil 10,000 times more actively blocks PDE5 than PDE3 – an enzyme found in the heart and blood vessels.
It is not recommended for people with heart and vascular disease, priapism, cavernous fibrosis, leukemia.
If the dose is exceeded Esculap may cause such side effects as headaches, dizziness, back pain. It is not recommended for people with heart and vascular disease, priapism, cavernous fibrosis, leukemia.
In the male tadalafil study at a daily dose of 20 mg, there was no clinically significant effect of the drug on sperm count, sperm motility and sperm count and concentration.